First-author publication in SCI-ranked international journal for research on ovarian cancer treatment development / Jae Eun Lee (Biomedical Science major 21)
- 24.10.28 / 이정민
Kookmin University (President Jung Seung-ryul) announced that a paper by Lee Jae-eun, a fourth-year biomedicine major in the College of Applied Chemistry, School of Science and Technology, and her advisor, Heo, Kyun, has been published in the SCI-level international journal Anticancer Research.
(From left) Lee Jae-eun, a biomedical engineering major at Kookmin University's School of Applied Chemistry (first author), and Professor Heo, Kyun (corresponding author) (Provided by Kookmin University)
The researchers used more than 1,000 drugs approved by the U.S. Food and Drug Administration (US-FDA) to screen for drugs that inhibit the growth of ovarian cancer cells, and found that valrubicin, a drug previously used to treat bladder cancer, effectively inhibits the growth of ovarian cancer cells.
“This paper is a drug repositioning study that suggests the possibility that valrubicin could be developed as a treatment for ovarian cancer,” said lead author Professor Heo, Kyun Heo, a biomedical engineering major at Kookmin University's Department of Applied Chemistry. ”Through the support of the LINC 3.0 project, Undergraduate Research Participation Program (UROP) student Jae Eun Lee took the lead in conducting the research and writing the paper, and obtained meaningful research results.
Drug repositioning is the process of finding new therapeutic indications for existing licensed drugs. Since the drugs discovered through drug repositioning have already been tested for safety in humans, it is gaining more attention in the pharmaceutical industry as it can dramatically reduce the cost and time of drug development.
“This research was the result of about two years of undergraduate research participation program (UROP) and research internship program, and I was able to achieve good research results through the excellent support infrastructure of Kookmin University and Professor Heo Gyun who taught me a lot,” said Lee Jae-eun, the first author of the paper. ”I am very grateful to the school for giving me a great opportunity and to Professor Heo, Kyun for providing a lot of support in the process of developing an anti-cancer drug for ovarian cancer.”
The research was supported by the Korea Research Foundation Mid-Career Research Program of the Ministry of Science and ICT.
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First-author publication in SCI-ranked international journal for research on ovarian cancer treatment development / Jae Eun Lee (Biomedical Science major 21) |
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2024-10-28
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Kookmin University (President Jung Seung-ryul) announced that a paper by Lee Jae-eun, a fourth-year biomedicine major in the College of Applied Chemistry, School of Science and Technology, and her advisor, Heo, Kyun, has been published in the SCI-level international journal Anticancer Research.
“This paper is a drug repositioning study that suggests the possibility that valrubicin could be developed as a treatment for ovarian cancer,” said lead author Professor Heo, Kyun Heo, a biomedical engineering major at Kookmin University's Department of Applied Chemistry. ”Through the support of the LINC 3.0 project, Undergraduate Research Participation Program (UROP) student Jae Eun Lee took the lead in conducting the research and writing the paper, and obtained meaningful research results.
Drug repositioning is the process of finding new therapeutic indications for existing licensed drugs. Since the drugs discovered through drug repositioning have already been tested for safety in humans, it is gaining more attention in the pharmaceutical industry as it can dramatically reduce the cost and time of drug development.
“This research was the result of about two years of undergraduate research participation program (UROP) and research internship program, and I was able to achieve good research results through the excellent support infrastructure of Kookmin University and Professor Heo Gyun who taught me a lot,” said Lee Jae-eun, the first author of the paper. ”I am very grateful to the school for giving me a great opportunity and to Professor Heo, Kyun for providing a lot of support in the process of developing an anti-cancer drug for ovarian cancer.”
The research was supported by the Korea Research Foundation Mid-Career Research Program of the Ministry of Science and ICT.
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